Peri-Operative bile metabonomics changes of extrahepatic cholangiocarcinoma and prognosis analysis / 第二军医大学学报

Objective To screen for molecular markers associated with the prognosis of extrahepatic cholangiocarcinoma (EHCC) after radical excision by observing the difference of bile metabolomics during perioperative period. Methods Twenty-seven patients with EHCC, including 19 with hilar cholangiocarcinoma and 8 with distal cholangiocarcinoma, were included in this study. Their bile samples were collected before and 1, 7 days after operation. Metabonomics method using gas chromatograph